Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 5/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14659225 | 1.00 | SYK (0.49) | SYKPDGFRBPDGFRAHTR1AADRA1D | |
| SCHEMBL31328784 | 0.85 | SYK (0.42) | SYKPDGFRBPDGFRAHTR1AADRA1D | |
| SCHEMBL27980378 | 0.82 | SYK (0.64) | SYKPDGFRBPDGFRAKDM4EMEN1 | |
| SCHEMBL3971693 | 0.82 | SYK (0.49) | SYKPDGFRBPDGFRAHTR1AADRA1D | |
| SCHEMBL3971691 | 0.81 | SYK (0.48) | SYKPDGFRBPDGFRAHTR1AADRA1D | |
| SCHEMBL3968718 | 0.79 | SYK (0.47) | SYKPDGFRBPDGFRAHTR1AADRA1D | |
| SCHEMBL7354335 | 0.79 | SYK (0.44) | SYKPDGFRBPDGFRAHTR1AADRA1D | |
| SCHEMBL25467033 | 0.79 | MAPT (0.45) | MEN1KMT2AHTTTDP1MAPT | |
| SCHEMBL31298565 | 0.79 | HTR1A (0.58) | HTR1AADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL2996402 | 0.79 | HTR1A (0.58) | HTR1AADRA1DADRA1AADRA1BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |
| EP-4055014-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | Yuhan Corporation (KR) | 2022-09-14 | — | — | EP | disclosed |