Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | USP14 | P54578 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720679 | 1.00 | NOTUM (0.47) | NOTUMPOLBMAPK1USP14ALDH1A1 | |
| SCHEMBL23245524 | 0.88 | POLB (0.46) | NOTUMPOLBMAPK1USP14ALDH1A1 | |
| SCHEMBL25712476 | 0.88 | MAPK1 (0.48) | NOTUMPOLBMAPK1USP14ALDH1A1 | |
| SCHEMBL31329464 | 0.88 | POLB (0.46) | NOTUMPOLBMAPK1USP14ALDH1A1 | |
| SCHEMBL23245292 | 0.86 | NOTUM (0.41) | NOTUMPOLBMAPK1USP14ALDH1A1 | |
| SCHEMBL31329459 | 0.86 | NOTUM (0.41) | NOTUMPOLBMAPK1USP14ALDH1A1 | |
| SCHEMBL31329473 | 0.82 | USP14 (0.50) | NOTUMPOLBMAPK1USP14ALDH1A1 | |
| SCHEMBL23245307 | 0.82 | USP14 (0.50) | NOTUMPOLBMAPK1USP14ALDH1A1 | |
| SCHEMBL16720694 | 0.81 | NOTUM (0.49) | NOTUMPOLBMAPK1USP14ALDH1A1 | |
| SCHEMBL25712451 | 0.81 | POLB (0.51) | NOTUMPOLBMAPK1USP14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112585132-B | Proteasome activity enhancing compounds | 优曼尼蒂公司 | 2025-02-28 | — | — | CN | disclosed |