Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | USP14 | P54578 | 2/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23245524 | 1.00 | POLB (0.46) | POLBNOTUMMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL25712476 | 0.88 | MAPK1 (0.48) | POLBNOTUMMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16720679 | 0.88 | NOTUM (0.47) | POLBNOTUMMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31329454 | 0.88 | NOTUM (0.47) | POLBNOTUMMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31329473 | 0.82 | USP14 (0.50) | POLBNOTUMMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL23245307 | 0.82 | USP14 (0.50) | POLBNOTUMMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL23245292 | 0.81 | NOTUM (0.41) | POLBNOTUMMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31329459 | 0.81 | NOTUM (0.41) | POLBNOTUMMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL25712451 | 0.81 | POLB (0.51) | POLBNOTUMMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL23245570 | 0.80 | PTGS2 (0.43) | POLBNOTUMMAPK1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112585132-B | Proteasome activity enhancing compounds | 优曼尼蒂公司 | 2025-02-28 | — | — | CN | disclosed |