SCHEMBL31329795

SCHEMBL31329795

CS(=O)(=O)N1CCC2(CC1)CC(=O)c1ccccc1O2

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.62
SIGMAR1 Q99720 1/20 0.60
ATM Q13315 1/20 0.55
ADRA1D P25100 2/20 0.52
ADRA1A P35348 2/20 0.52
ADRA1B P35368 2/20 0.52
EPHX2 P34913 3/20 0.51
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
CA7 P43166 1/20 0.51
CA9 Q16790 1/20 0.51
HRH3 Q9Y5N1 1/20 0.50
CYP2C9 P11712 1/20 0.49
EPHX1 P07099 1/20 0.48
SCN5A Q14524 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13790914 1.00 L3MBTL1 (0.62) L3MBTL1SIGMAR1ATMADRA1DADRA1A
SCHEMBL742078 0.83 SIGMAR1 (0.65) L3MBTL1SIGMAR1ATMADRA1DADRA1A
SCHEMBL16503899 0.80 SIGMAR1 (0.65) L3MBTL1SIGMAR1ATMADRA1DADRA1A
SCHEMBL9963309 0.80 SIGMAR1 (0.61) L3MBTL1SIGMAR1ATMADRA1DADRA1A
SCHEMBL29964739 0.80 SIGMAR1 (0.61) L3MBTL1SIGMAR1ATMADRA1DADRA1A
SCHEMBL30538348 0.80 ATM (0.64) L3MBTL1SIGMAR1ATMADRA1DADRA1A
SCHEMBL2588053 0.78 SIGMAR1 (0.66) SIGMAR1ATMADRA1DADRA1AADRA1B
SCHEMBL3222598 0.78 SIGMAR1 (0.66) SIGMAR1ATMADRA1DADRA1AADRA1B
SCHEMBL619987 0.78 ATM (0.64) L3MBTL1SIGMAR1ATMADRA1DADRA1A
SCHEMBL11114131 0.78 ATM (0.64) L3MBTL1SIGMAR1ATMADRA1DADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119371410-A Chromone spiro compound and preparation method and application thereof 中国药科大学 2025-01-28 CN disclosed