Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 7/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.32 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.32 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31330161 | 0.84 | ALDH1A1 (0.35) | CYP2C9CYP2D6CYP3A4 | |
| SCHEMBL31330114 | 0.77 | CYP3A4 (0.31) | CYP2C9CYP2D6CYP3A4 | |
| SCHEMBL31329939 | 0.76 | KMT2A (0.38) | GAASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL17430753 | 0.75 | CYP2C9 (0.44) | CYP2C9CYP2D6GAASMN1; SMN2CYP3A4 | |
| SCHEMBL31330030 | 0.74 | CYP2C9 (0.37) | CYP2C9CYP2D6 | |
| SCHEMBL30720585 | 0.72 | CYP2C9 (0.36) | CYP2C9CYP2D6GAASMN1; SMN2CYP3A4 | |
| SCHEMBL28996370 | 0.70 | XDH (0.38) | CYP2C9CYP2D6GAASMN1; SMN2CYP4Z1 | |
| SCHEMBL31329821 | 0.69 | CYP2C9 (0.35) | CYP2C9CYP2D6CYP3A4 | |
| SCHEMBL29756186 | 0.69 | CYP2C9 (0.46) | CYP2C9CYP2D6GAASMN1; SMN2CYP3A4 | |
| SCHEMBL28852779 | 0.69 | CYP2C9 (0.35) | CYP2C9CYP2D6GAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024249817-A1 | TRICYCLIC PKMYT1 KINASE INHIBITORS | ENLIVEN INC. (US) | 2024-12-05 | — | — | WO | disclosed |