Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31530967 | 0.87 | MAPKAPK2 (0.40) | MAPKAPK2TGFBR1GSK3BDYRK1ADGAT1 | |
| SCHEMBL16147173 | 0.82 | ATR (0.45) | MAPKAPK2GSK3BDYRK1ASCN9AATR | |
| SCHEMBL31248850 | 0.82 | ATR (0.45) | MAPKAPK2GSK3BDYRK1ASCN9AATR | |
| SCHEMBL21590399 | 0.79 | CYP1A2 (0.41) | GSK3BDYRK1ACYP3A4CYP2C19SCN9A | |
| SCHEMBL19013519 | 0.78 | TGFBR1 (0.44) | MAPKAPK2TGFBR1GSK3BDYRK1ADGAT1 | |
| SCHEMBL31235341 | 0.78 | LCK (0.39) | MAPKAPK2GSK3BDYRK1ASCN9AATR | |
| SCHEMBL31093794 | 0.77 | MAPKAPK2 (0.39) | MAPKAPK2TGFBR1DGAT1GAACYP3A4 | |
| SCHEMBL31330039 | 0.76 | MAPKAPK2 (0.38) | MAPKAPK2TGFBR1DGAT1TMIGD3ADORA1 | |
| SCHEMBL31323628 | 0.76 | MAPKAPK2 (0.40) | MAPKAPK2TGFBR1DGAT1TMIGD3ADORA1 | |
| SCHEMBL15263847 | 0.76 | TGFBR1 (0.42) | MAPKAPK2TGFBR1GSK3BDYRK1ADGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024249817-A1 | TRICYCLIC PKMYT1 KINASE INHIBITORS | ENLIVEN INC. (US) | 2024-12-05 | — | — | WO | disclosed |