Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30898847 | 0.79 | CSNK2A2 (0.43) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL31330120 | 0.75 | KDM4E (0.44) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL31330123 | 0.75 | ALDH1A1 (0.43) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1697934 | 0.72 | CSNK2A1 (0.40) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL31330011 | 0.72 | KDM4E (0.44) | KDM4EPARP1TNKSPARP6PARP2 | |
| SCHEMBL25099251 | 0.71 | KDM4E (0.54) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL22912783 | 0.71 | KDM4E (0.57) | KDM4EALDH1A1HPGDCSNK2A1HSD17B10 | |
| SCHEMBL22912821 | 0.69 | KDM4E (0.45) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29394062 | 0.69 | KDM4E (0.45) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL25402627 | 0.67 | CSNK2A2 (0.43) | KDM4EALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371425-A | Nitrogen-containing heterocyclic compound, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2025-01-28 | — | — | CN | disclosed |