SCHEMBL31330123

SCHEMBL31330123

CCc1cc2nc(C(=O)OC)sc2[nH]c1=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
GABRA1 P14867 2/20 0.35
GABRA5 P31644 2/20 0.35
GABRA3 P34903 2/20 0.35
GABRA2 P47869 2/20 0.35
GABRA6 Q16445 2/20 0.35
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35
GABRB1 P18505 1/20 0.35
GABRG2 P18507 1/20 0.35
GABRB3 P28472 1/20 0.35
GABRB2 P47870 1/20 0.35
GABRA4 P48169 1/20 0.35
GABRE P78334 1/20 0.35
GABRG1 Q8N1C3 1/20 0.35
GABRG3 Q99928 1/20 0.35
GABRQ Q9UN88 1/20 0.35
HSD17B10 Q99714 1/20 0.34
DYRK1A Q13627 2/20 0.34
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31330134 0.78 GRIN2D (0.36) ALDH1A1KDM4EHCAR2PDE3BPDE3A
SCHEMBL31330132 0.75 KDM4E (0.40) ALDH1A1GABRA1GABRA5GABRA3GABRA2
SCHEMBL31330088 0.74 HCAR2 (0.39) RAB9AHCAR2
SCHEMBL31330040 0.74 SMN1; SMN2 (0.41) ALDH1A1HSD17B10RAB9ASMN1; SMN2MAPT
SCHEMBL31330115 0.73 GRIN2D (0.34) ALDH1A1KDM4ESMN1; SMN2HCAR2PDE3B
SCHEMBL26451159 0.71 HCAR2 (0.35) ALDH1A1HCAR2L3MBTL1
SCHEMBL31330075 0.71 RAB9A (0.35) ALDH1A1KDM4EHTTRAB9ASMN1; SMN2
SCHEMBL31071340 0.68 PDE3B (0.41) GABRA1GABRA5GABRA3GABRA2GABRA6
SCHEMBL20832544 0.68 ALDH1A1 (0.67) ALDH1A1KDM4EHTTRAB9ASMN1; SMN2
SCHEMBL24649822 0.68 PARP1 (0.44) PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119371425-A Nitrogen-containing heterocyclic compound, preparation method and medical application thereof 中国医药研究开发中心有限公司 2025-01-28 CN disclosed