Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 7/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29419572 | 0.89 | PAOX (0.36) | KDM4EALDH1A1SMN1; SMN2TSHRCYP1A2 | |
| SCHEMBL31330095 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1SMN1; SMN2TSHRCYP1A2 | |
| SCHEMBL26901753 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1SMN1; SMN2TSHRCYP1A2 | |
| Hydrochloric Acid SCHEMBL31191863 | 0.84 | ALDH1A1 (0.38) | KDM4EALDH1A1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL16975008 | 0.83 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2TSHRCYP1A2 | |
| SCHEMBL5247338 | 0.83 | ACHE (0.46) | KDM4EALDH1A1SMN1; SMN2TSHRCYP1A2 | |
| SCHEMBL6290135 | 0.83 | KDM4E (0.45) | KDM4EALDH1A1SMN1; SMN2TSHRCYP1A2 | |
| SCHEMBL5249867 | 0.83 | ACHE (0.46) | KDM4EALDH1A1SMN1; SMN2TSHRCYP1A2 | |
| SCHEMBL26553592 | 0.82 | CYP1A2 (0.49) | KDM4EALDH1A1SMN1; SMN2TSHRCYP1A2 | |
| SCHEMBL11140956 | 0.81 | TSHR (0.48) | KDM4EALDH1A1TSHRCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250135006-A1 | AMPHIPHILIC TLR7/8 ADJUVANTS AND USES THEREOF | PFIZER (US) | 2025-05-01 | — | — | US | disclosed |
| WO-2025012756-A1 | AMPHIPHILIC TLR7/8 ADJUVANTS AND USES THEREOF | PFIZER INC. (US) | 2025-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250135006-A1 | AMPHIPHILIC TLR7/8 ADJUVANTS AND USES THEREOF | TLR7, TLR8, TLR9 | KDM4E 3504/4885ALDH1A1 3881/4885SMN1; SMN2 2681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.