SCHEMBL31330488

SCHEMBL31330488

CCCCNc1ccc2cc(OC)ccc2n1

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 8/20 0.55
NCF1 P14598 1/20 0.50
NQO1 P15559 1/20 0.48
BCHE P06276 8/20 0.47
ACHE P22303 8/20 0.47
TLR8 Q9NR97 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28155719 0.86 NCF1 (0.54) HTR1ANCF1NQO1BCHEACHE
SCHEMBL11755720 0.85 HTR1A (0.55) HTR1ANCF1NQO1
SCHEMBL11761733 0.82 HTR1A (0.50) HTR1ANCF1NQO1
Hydrochloric Acid SCHEMBL29522758 0.81 MEN1 (0.53) HTR1ANCF1NQO1
SCHEMBL11761730 0.80 HTR1A (0.48) HTR1ANCF1NQO1
SCHEMBL11758587 0.78 HTR1A (0.49) HTR1ANCF1NQO1BCHEACHE
Nitric Acid SCHEMBL11758582 0.78 HTR1A (0.49) HTR1ANCF1NQO1
SCHEMBL20226874 0.77 ABCB1 (0.48) NQO1BCHETLR8
SCHEMBL27873830 0.77 EGFR (0.47) HTR1ABCHEACHETLR8
SCHEMBL3956730 0.76 TLR8 (0.56) HTR1ANCF1BCHETLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720081-A1 CONJUGATE COMPOSITIONS COMPRISING PHOSPHORYL GUANIDINE LINKAGES AND USES THEREOF Avidity Biosciences, Inc. (US) 2026-04-08 EP disclosed
WO-2024249944-A1 CONJUGATE COMPOSITIONS COMPRISING PHOSPHORYL GUANIDINE LINKAGES AND USES THEREOF AVIDITY BIOSCIENCES, INC. (US) 2024-12-05 WO disclosed