Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31330465 | 0.95 | GAA (0.46) | GAAALOX15EGFRPIK3CAGRM1 | |
| SCHEMBL31278641 | 0.79 | EGFR (0.40) | EGFRRXFP1ALDH1A1LMNA | |
| SCHEMBL26988300 | 0.79 | EGFR (0.40) | EGFRRXFP1ALDH1A1LMNA | |
| SCHEMBL31330439 | 0.75 | HPGD (0.38) | GAAEGFRRXFP1ALDH1A1CYP1A2 | |
| SCHEMBL31330668 | 0.75 | EGFR (0.35) | EGFRHCAR1 | |
| SCHEMBL31330656 | 0.74 | GAA (0.40) | GAAALOX15GRM1MAT2AALDH1A1 | |
| SCHEMBL31330633 | 0.73 | PARG (0.38) | — | |
| SCHEMBL31330708 | 0.71 | ADORA2A (0.40) | CRHBPCRHR2MAPK1LMNA | |
| SCHEMBL31330602 | 0.71 | ADORA2A (0.37) | CRHBPCRHR2MAPK1LMNA | |
| SCHEMBL31330522 | 0.71 | CNR1 (0.41) | EGFRPIK3CACDK9ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720061-A1 | TREM2 AGONISTS | F. Hoffmann-La Roche AG (CH) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246018-A1 | TREM2 AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-12-05 | — | — | WO | disclosed |