Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 9/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 8/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 8/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.34 |
| ▸ | IKZF3 | Q9UKT9 | 5/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31331332 | 0.91 | PBRM1 (0.51) | PBRM1SMARCA2SMARCA4NR1I2DRD2 | |
| SCHEMBL31331350 | 0.88 | PBRM1 (0.38) | PBRM1SMARCA2SMARCA4NR1I2DRD2 | |
| SCHEMBL31331532 | 0.86 | PBRM1 (0.37) | PBRM1SMARCA2SMARCA4NR1I2CRBN | |
| SCHEMBL31101071 | 0.84 | PBRM1 (0.41) | PBRM1SMARCA2SMARCA4NR1I2DRD2 | |
| SCHEMBL31331277 | 0.82 | CRBN (0.36) | PBRM1SMARCA2SMARCA4NR1I2CRBN | |
| SCHEMBL31102957 | 0.82 | PBRM1 (0.41) | PBRM1SMARCA2SMARCA4NR1I2DRD2 | |
| SCHEMBL31101161 | 0.81 | SMARCA2 (0.39) | PBRM1SMARCA2SMARCA4NR1I2DRD2 | |
| SCHEMBL31330765 | 0.81 | PBRM1 (0.40) | PBRM1SMARCA2SMARCA4NR1I2DRD2 | |
| SCHEMBL31279210 | 0.80 | PARP1 (0.49) | DRD2HTR1ADDB1CRBNIKZF3 | |
| SCHEMBL31278850 | 0.80 | ADRA1D (0.42) | DRD2HTR1ADDB1CRBNIKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024245443-A1 | COMPOUND BASED ON OXOISOINDOLINYL SUBSTITUTED TETRAHYDRO-2-PYRIMIDONE, AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-12-05 | — | — | WO | claimed |
| WO-2024245443-A1 | COMPOUND BASED ON OXOISOINDOLINYL SUBSTITUTED TETRAHYDRO-2-PYRIMIDONE, AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-12-05 | — | — | WO | disclosed |