SCHEMBL31331983

SCHEMBL31331983

COc1ccc2cccc(CCN(C)C)c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 4/20 1.00
MTNR1A P48039 13/20 0.71
MTNR1B P49286 4/20 0.71
HTR2C P28335 2/20 0.58
HTR2B P41595 2/20 0.58
HTR6 P50406 2/20 0.57
HTR3E A5X5Y0 1/20 0.56
HTR3B O95264 1/20 0.56
CYP1A2 P05177 1/20 0.56
HTR1A P08908 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56
HTR1D P28221 1/20 0.56
HTR1B P28222 1/20 0.56
HTR1E P28566 1/20 0.56
HTR1F P30939 1/20 0.56
HTR7 P34969 1/20 0.56
HTR3A P46098 1/20 0.56
HTR5A P47898 1/20 0.56
HTR4 Q13639 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8021734 1.00 HTR2A (1.00) HTR2AMTNR1AMTNR1BHTR2CHTR2B
Hydrochloric Acid SCHEMBL8573356 0.98 HTR2A (0.97) HTR2AMTNR1AMTNR1BHTR2CHTR2B
SCHEMBL27365823 0.87 HTR2A (1.00) HTR2AMTNR1AMTNR1BHTR2CHTR2B
Hydrochloric Acid SCHEMBL31499094 0.86 HTR2A (0.97) HTR2AMTNR1AMTNR1BHTR2CHTR2B
SCHEMBL27365826 0.86 HTR2A (0.75) HTR2AMTNR1AMTNR1BHTR2CHTR2B
SCHEMBL27365825 0.86 HTR2A (0.82) HTR2AMTNR1AMTNR1BHTR2CHTR2B
SCHEMBL27365817 0.85 HTR2A (0.78) HTR2AMTNR1AMTNR1BHTR2CHTR2B
SCHEMBL15495138 0.85 HTR2A (0.73) HTR2AMTNR1AMTNR1BHTR2CHTR2B
Hydrochloric Acid SCHEMBL31332138 0.85 HTR2A (0.81) HTR2AMTNR1AMTNR1BHTR2CHTR2B
Hydrochloric Acid SCHEMBL31332085 0.85 HTR2A (0.73) HTR2AMTNR1AMTNR1BHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333371-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-10-30 US disclosed
EP-4532462-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-04-09 EP disclosed
CN-119384406-A Compounds of formula (I) 赛洛私人有限公司 2025-01-28 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333371-A1 COMPOUNDS SDHA, PYGB, SLC18A2 HTR2A 225/4885MTNR1A 1247/4885MTNR1B 757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.