SCHEMBL31332016

SCHEMBL31332016

CSCCC(NC(=O)C(CO)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(N)CO)C(=O)NC(CCC(=O)O)C(=O)NC(Cc1cnc[nH]1)C(=O)NC(Cc1ccccc1)C(=O)NC(CCCNC(=N)N)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCC(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)NC(C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)N1CCCC1C(=O)NC(C(=O)NC(CCCCN)C(=O)NC(C(=O)NC(Cc1ccc(O)cc1)C(=O)N1CCCC1C(=O)NC(CCCCNC(=O)CCCCC1SCC2NC(=O)NC21)C(N)=O)C(C)C)C(C)C)C(C)C

nearest known ligand 0.71

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MC4R P32245 2/20 0.71
MC5R P33032 2/20 0.71
MC3R P41968 2/20 0.71
MC1R Q01726 2/20 0.71
CXCR4 P61073 9/20 0.66
PTH1R Q03431 5/20 0.62
C5AR1 P21730 1/20 0.62
AKT1 P31749 1/20 0.60
GLP1R P43220 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cosyntropin SCHEMBL15960130 0.90 MC4R (0.81) MC4RMC5RMC3RMC1RCXCR4
Cosyntropin SCHEMBL33367 0.90 MC4R (0.81) MC4RMC5RMC3RMC1RCXCR4
Cosyntropin SCHEMBL29410267 0.90 MC4R (0.81) MC4RMC5RMC3RMC1RCXCR4
SCHEMBL29519503 0.90 MC4R (0.81) MC4RMC5RMC3RMC1RCXCR4
SCHEMBL31477752 0.90 MC4R (0.83) MC4RMC5RMC3RMC1RCXCR4
SCHEMBL29622934 0.89 MC4R (0.83) MC4RMC5RMC3RMC1RCXCR4
Giractide SCHEMBL1650268 0.88 MC4R (0.85) MC4RMC5RMC3RMC1RCXCR4
SCHEMBL29385997 0.88 MC4R (0.84) MC4RMC5RMC3RMC1RCXCR4
SCHEMBL29382991 0.88 MC4R (0.84) MC4RMC5RMC3RMC1RCXCR4
Tosactide SCHEMBL29353880 0.88 MC4R (0.77) MC4RMC5RMC3RMC1RCXCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME LONGEVITY BIOTECH, INC. 2024-11-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME SCTR, GIPR, APLNR MC4R 528/4885MC5R 722/4885MC3R 323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.