Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31332613 | 0.89 | ALDH1A1 (0.46) | EPHX2NPC1RAB9AEPHX1TDP1 | |
| SCHEMBL31332634 | 0.85 | EPHX1 (0.54) | EPHX2NPC1EPHX1L3MBTL1ALDH1A1 | |
| SCHEMBL31332705 | 0.85 | EPHX1 (0.54) | EPHX2NPC1EPHX1L3MBTL1ALDH1A1 | |
| SCHEMBL31332801 | 0.81 | EPHX2 (0.49) | EPHX2NPC1RAB9AEPHX1L3MBTL1 | |
| SCHEMBL31332653 | 0.81 | EPHX2 (0.49) | EPHX2NPC1RAB9AEPHX1L3MBTL1 | |
| SCHEMBL31332799 | 0.80 | POLB (0.53) | EPHX2NPC1RAB9AEPHX1L3MBTL1 | |
| SCHEMBL31332624 | 0.78 | TAAR1 (0.39) | EPHX2EPHX1L3MBTL1ALDH1A1GAA | |
| SCHEMBL31332732 | 0.78 | TAAR1 (0.39) | EPHX2EPHX1L3MBTL1ALDH1A1GAA | |
| SCHEMBL31332770 | 0.76 | NPC1 (0.44) | NPC1RAB9AALDH1A1HPGDPOLB | |
| SCHEMBL31332716 | 0.75 | KMT2A (0.37) | RAB9AALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709708-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ANGELINI PHARMA S.P.A. (IT) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233603-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ICAGEN, LLC (US) | 2024-11-14 | — | — | WO | disclosed |