Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DGAT2 | Q96PD7 | 4/20 | 0.40 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31332782 | 0.91 | NPC1 (0.39) | NPC1RAB9APOLBSMN1; SMN2DGAT2 | |
| SCHEMBL31332623 | 0.90 | NPC1 (0.39) | NPC1RAB9APOLBSMN1; SMN2DGAT2 | |
| SCHEMBL31332734 | 0.77 | PTGDR2 (0.34) | NPC1RAB9ATP53HTTLMNA | |
| SCHEMBL31332706 | 0.76 | EPHX2 (0.53) | NPC1RAB9APOLBSMN1; SMN2HPGD | |
| SCHEMBL31332732 | 0.76 | TAAR1 (0.39) | ALDH1A1 | |
| SCHEMBL31332624 | 0.76 | TAAR1 (0.39) | ALDH1A1 | |
| SCHEMBL31332790 | 0.75 | TAAR1 (0.37) | ALDH1A1SLC6A3 | |
| SCHEMBL31332653 | 0.74 | EPHX2 (0.49) | NPC1RAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL31332801 | 0.74 | EPHX2 (0.49) | NPC1RAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL31332705 | 0.74 | EPHX1 (0.54) | NPC1POLBTP53HTTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709708-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ANGELINI PHARMA S.P.A. (IT) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233603-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ICAGEN, LLC (US) | 2024-11-14 | — | — | WO | disclosed |