Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 8/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31332869 | 0.93 | HSD11B1 (0.38) | HSD11B1ICMTCCR2KCNH2BACE1 | |
| SCHEMBL31332694 | 0.91 | HSD11B1 (0.39) | HSD11B1ICMTCCR2KCNH2BACE1 | |
| SCHEMBL31332837 | 0.85 | HSD11B1 (0.39) | HSD11B1ICMTBACE1GRIN2BMCHR1 | |
| SCHEMBL31332643 | 0.84 | HSD11B1 (0.41) | HSD11B1ICMTCCR2KCNH2GRIN2B | |
| SCHEMBL31332651 | 0.84 | DGAT2 (0.48) | HSD11B1GRIN2B | |
| SCHEMBL31332744 | 0.84 | DGAT2 (0.48) | HSD11B1GRIN2B | |
| SCHEMBL31332714 | 0.84 | HSD11B1 (0.37) | HSD11B1ICMTGRIN2BMCHR1 | |
| SCHEMBL31332702 | 0.84 | DGAT2 (0.41) | HSD11B1GRIN2BMCHR1 | |
| SCHEMBL31332803 | 0.83 | HSD11B1 (0.38) | HSD11B1ICMTGRIN2BMCHR1 | |
| SCHEMBL31332781 | 0.83 | HSD11B1 (0.38) | HSD11B1ICMTBACE1GRIN2BMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709708-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ANGELINI PHARMA S.P.A. (IT) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233603-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ICAGEN, LLC (US) | 2024-11-14 | — | — | WO | disclosed |