Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 2/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2701320 | 0.80 | CHRNB2 (0.50) | CHRNB2CHRNA4NOS2TACR1SLC7A5 | |
| SCHEMBL10858664 | 0.80 | AOC3 (0.51) | CHRNB2CHRNA4AOC3PNMTNOS2 | |
| SCHEMBL10727832 | 0.78 | CHRNB2 (0.48) | CHRNB2CHRNA4AOC3PNMTNOS2 | |
| SCHEMBL7486969 | 0.77 | AOC3 (0.52) | CHRNB2CHRNA4AOC3PNMTNOS2 | |
| SCHEMBL7486961 | 0.77 | AOC3 (0.52) | CHRNB2CHRNA4AOC3PNMTNOS2 | |
| SCHEMBL10862916 | 0.77 | AOC3 (0.49) | CHRNB2CHRNA4AOC3PNMTNOS2 | |
| SCHEMBL10860748 | 0.76 | AOC3 (0.51) | CHRNB2CHRNA4AOC3PNMTNOS2 | |
| SCHEMBL31332868 | 0.76 | CHRNB2 (0.46) | CHRNB2CHRNA4AOC3PNMTNOS2 | |
| SCHEMBL10859369 | 0.76 | CHRNB2 (0.70) | CHRNB2CHRNA4AOC3PNMTNOS2 | |
| SCHEMBL10734651 | 0.76 | CHRNB2 (0.46) | CHRNB2CHRNA4AOC3PNMTNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709708-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ANGELINI PHARMA S.P.A. (IT) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233603-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ICAGEN, LLC (US) | 2024-11-14 | — | — | WO | disclosed |