SCHEMBL31332767

SCHEMBL31332767

COC(C)(CNC(=O)NCc1cccc(F)c1)c1cccc(Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.50
OPRL1 P41146 1/20 0.50
EPHX2 P34913 2/20 0.47
IDH1 O75874 1/20 0.44
RAB9A P51151 3/20 0.43
ANPEP P15144 1/20 0.42
NPC1 O15118 1/20 0.41
LMNA P02545 2/20 0.40
APEX1 P27695 1/20 0.40
HPGD P15428 1/20 0.40
CNR1 P21554 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
MAPK1 P28482 2/20 0.40
MEN1 O00255 1/20 0.40
PLA2G1B P04054 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
GAA P10253 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31332728 0.88 IDH1 (0.44) OPRM1EPHX2IDH1RAB9ANPC1
SCHEMBL31332632 0.80 LMNA (0.50) RAB9ANPC1LMNAHPGDSMN1; SMN2
SCHEMBL31332754 0.79 KMT2A (0.56) EPHX2RAB9ANPC1LMNACNR1
SCHEMBL31332742 0.79 EPHX2 (0.49) EPHX2RAB9ALMNAHPGDSMN1; SMN2
SCHEMBL31332818 0.78 EPHX1 (0.50) EPHX2
SCHEMBL31332799 0.77 POLB (0.53) EPHX2RAB9ANPC1SMN1; SMN2MAPK1
SCHEMBL31332636 0.76 FPR2 (0.52) RAB9ANPC1LMNACNR1SMN1; SMN2
SCHEMBL31332634 0.75 EPHX1 (0.54) EPHX2NPC1MAPK1MEN1CYP1A2
SCHEMBL31332705 0.75 EPHX1 (0.54) EPHX2NPC1MAPK1MEN1CYP1A2
SCHEMBL31332801 0.74 EPHX2 (0.49) EPHX2RAB9ANPC1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709708-A1 NOVEL CARBOXAMIDE DERIVATIVES ANGELINI PHARMA S.P.A. (IT) 2026-03-18 EP disclosed
WO-2024233603-A1 NOVEL CARBOXAMIDE DERIVATIVES ICAGEN, LLC (US) 2024-11-14 WO disclosed