Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 3/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31332770 | 0.91 | NPC1 (0.44) | NPC1POLBRAB9ASMN1; SMN2CETP | |
| SCHEMBL31332623 | 0.89 | NPC1 (0.39) | NPC1POLBRAB9ASMN1; SMN2CETP | |
| SCHEMBL31332790 | 0.74 | TAAR1 (0.37) | ALDH1A1KCNH2 | |
| SCHEMBL31332891 | 0.73 | SIGMAR1 (0.45) | POLBALDH1A1DGAT2TP53 | |
| SCHEMBL31332854 | 0.73 | SIGMAR1 (0.53) | ALDH1A1DGAT2MGAT2TSHR | |
| SCHEMBL31332732 | 0.73 | TAAR1 (0.39) | ALDH1A1 | |
| SCHEMBL31332624 | 0.73 | TAAR1 (0.39) | ALDH1A1 | |
| SCHEMBL31332799 | 0.72 | POLB (0.53) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL31332620 | 0.72 | EPHX2 (0.40) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL31332801 | 0.72 | EPHX2 (0.49) | NPC1RAB9ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709708-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ANGELINI PHARMA S.P.A. (IT) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233603-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ICAGEN, LLC (US) | 2024-11-14 | — | — | WO | disclosed |