Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | GPR88 | Q9GZN0 | 7/20 | 0.45 |
| ▸ | ITK | Q08881 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1207556 | 1.00 | RIPK1 (0.48) | RIPK1FFAR1GPR88ITKNR4A2 | |
| SCHEMBL29730159 | 1.00 | RIPK1 (0.48) | RIPK1FFAR1GPR88ITKNR4A2 | |
| SCHEMBL2518996 | 1.00 | RIPK1 (0.48) | RIPK1FFAR1GPR88ITKNR4A2 | |
| SCHEMBL13167851 | 1.00 | RIPK1 (0.48) | RIPK1FFAR1GPR88ITKNR4A2 | |
| SCHEMBL3596616 | 1.00 | RIPK1 (0.48) | RIPK1FFAR1GPR88ITKNR4A2 | |
| SCHEMBL22092529 | 0.88 | GRM5 (0.42) | RIPK1FFAR1GPR88ITKLMNA | |
| SCHEMBL30243669 | 0.84 | GPR88 (0.45) | RIPK1GPR88ITKNPC1MAPT | |
| SCHEMBL29295352 | 0.84 | ITK (0.46) | RIPK1GPR88ITKNPC1MAPT | |
| SCHEMBL15219719 | 0.84 | ITK (0.46) | RIPK1GPR88ITKNPC1MAPT | |
| SCHEMBL27885579 | 0.81 | ITK (0.40) | RIPK1GPR88ITKFFAR4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709708-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ANGELINI PHARMA S.P.A. (IT) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233603-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ICAGEN, LLC (US) | 2024-11-14 | — | — | WO | disclosed |