Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31332854 | 0.94 | SIGMAR1 (0.53) | SIGMAR1DGAT2ALDH1A1LMNAMEN1 | |
| SCHEMBL31332805 | 0.86 | NAMPT (0.53) | SIGMAR1DGAT2NAMPT | |
| SCHEMBL31332729 | 0.84 | SIGMAR1 (0.38) | SIGMAR1LMNAMEN1KMT2A | |
| SCHEMBL31332790 | 0.82 | TAAR1 (0.37) | ALDH1A1 | |
| SCHEMBL31332624 | 0.80 | TAAR1 (0.39) | ALDH1A1L3MBTL1 | |
| SCHEMBL31332732 | 0.80 | TAAR1 (0.39) | ALDH1A1L3MBTL1 | |
| SCHEMBL31332715 | 0.79 | SIGMAR1 (0.50) | SIGMAR1DGAT2HTTALDH1A1LMNA | |
| SCHEMBL31332717 | 0.77 | SIGMAR1 (0.53) | SIGMAR1HTTALDH1A1TDP1LMNA | |
| SCHEMBL31332799 | 0.76 | POLB (0.53) | HTTALDH1A1POLBL3MBTL1MEN1 | |
| SCHEMBL5675747 | 0.73 | ALDH1A1 (0.49) | DGAT2ALDH1A1LMNANAMPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709708-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ANGELINI PHARMA S.P.A. (IT) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233603-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ICAGEN, LLC (US) | 2024-11-14 | — | — | WO | disclosed |