SCHEMBL31333323

SCHEMBL31333323

O=C1CCC(N2Cc3cc(OC4CCN(C(=O)C5CCNCC5)CC4)ccc3C2=O)C(=O)N1

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 11/20 0.55
▸ CSNK1A1 P48729 2/20 0.49
▸ IKZF2 Q9UKS7 7/20 0.47
▸ WIZ O95785 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30273536 0.89 CRBN (0.65) CRBNCSNK1A1IKZF2WIZ
SCHEMBL20046231 0.89 CRBN (0.65) CRBNCSNK1A1IKZF2WIZ
SCHEMBL20234306 0.89 CRBN (0.65) CRBNCSNK1A1IKZF2WIZ
SCHEMBL31333321 0.88 CRBN (0.52) CRBNCSNK1A1IKZF2WIZ
SCHEMBL31334312 0.88 CRBN (0.49) CRBNCSNK1A1IKZF2WIZ
SCHEMBL31333806 0.87 CRBN (0.55) CRBNCSNK1A1IKZF2WIZ
SCHEMBL31333471 0.86 IKZF2 (0.60) CRBNCSNK1A1IKZF2WIZ
SCHEMBL31070701 0.85 CRBN (0.61) CRBNCSNK1A1IKZF2WIZ
SCHEMBL30919855 0.85 CRBN (0.56) CRBNCSNK1A1IKZF2WIZ
SCHEMBL27146887 0.85 CRBN (0.58) CRBNCSNK1A1IKZF2WIZ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 — — EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 — — WO disclosed
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