SCHEMBL31333471

SCHEMBL31333471

O=C1CCC(N2Cc3cc(OC4CCN(C5CCNCC5)CC4)ccc3C2=O)C(=O)N1

nearest known ligand 0.60

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ IKZF2 Q9UKS7 6/20 0.60
▸ CRBN Q96SW2 10/20 0.58
▸ HRH3 Q9Y5N1 2/20 0.54
▸ WIZ O95785 2/20 0.47
▸ CSNK1A1 P48729 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20046231 0.91 CRBN (0.65) IKZF2CRBNWIZCSNK1A1
SCHEMBL20234306 0.91 CRBN (0.65) IKZF2CRBNWIZCSNK1A1
SCHEMBL30273536 0.91 CRBN (0.65) IKZF2CRBNWIZCSNK1A1
SCHEMBL20231482 0.89 CRBN (0.58) IKZF2CRBNWIZCSNK1A1
SCHEMBL24817738 0.89 CRBN (0.58) IKZF2CRBNWIZCSNK1A1
SCHEMBL31070701 0.88 CRBN (0.61) IKZF2CRBNWIZCSNK1A1
SCHEMBL31334235 0.86 IKZF2 (0.57) IKZF2CRBNWIZ
SCHEMBL31333323 0.86 CRBN (0.55) IKZF2CRBNWIZCSNK1A1
SCHEMBL31334496 0.86 CRBN (0.57) IKZF2CRBNWIZ
SCHEMBL20231670 0.85 CRBN (0.63) IKZF2CRBNWIZCSNK1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 — — EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 — — WO disclosed
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