SCHEMBL31334312

SCHEMBL31334312

CC(C)(C)OC(=O)N1CCC(C(=O)N2CCC(Oc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)CC2)CC1

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 10/20 0.49
▸ WIZ O95785 1/20 0.46
▸ IKZF2 Q9UKS7 4/20 0.45
▸ ALK Q9UM73 1/20 0.45
▸ HRH3 Q9Y5N1 1/20 0.45
▸ CSNK1A1 P48729 2/20 0.44
▸ PRMT5 O14744 1/20 0.44
▸ WDR77 Q9BQA1 1/20 0.44
▸ GPR119 Q8TDV5 2/20 0.44
▸ DDB1 Q16531 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20046226 0.95 CRBN (0.54) CRBNWIZIKZF2ALKHRH3
SCHEMBL30273649 0.95 CRBN (0.54) CRBNWIZIKZF2ALKHRH3
SCHEMBL31333342 0.91 IKZF2 (0.55) CRBNWIZIKZF2ALKHRH3
SCHEMBL31413474 0.90 CRBN (0.52) CRBNWIZIKZF2CSNK1A1DDB1
SCHEMBL32669075 0.90 CRBN (0.52) CRBNWIZIKZF2CSNK1A1DDB1
SCHEMBL31333603 0.89 IKZF2 (0.53) CRBNWIZIKZF2ALKHRH3
SCHEMBL31334533 0.89 CRBN (0.49) CRBNWIZIKZF2ALKHRH3
SCHEMBL31334319 0.88 CRBN (0.49) CRBNWIZIKZF2PRMT5WDR77
SCHEMBL31334749 0.88 CRBN (0.47) CRBNWIZIKZF2ALKCSNK1A1
SCHEMBL20046261 0.88 CRBN (0.55) CRBNWIZIKZF2CSNK1A1DDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 — — EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 — — WO disclosed
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