SCHEMBL31333342

SCHEMBL31333342

CC(C)(C)OC(=O)N1CCC(N2CCC(Oc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)CC2)CC1

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ IKZF2 Q9UKS7 3/20 0.55
▸ HRH3 Q9Y5N1 3/20 0.52
▸ CRBN Q96SW2 9/20 0.49
▸ WIZ O95785 1/20 0.46
▸ GPR119 Q8TDV5 2/20 0.45
▸ ALK Q9UM73 1/20 0.45
▸ DDB1 Q16531 1/20 0.45
▸ CSNK1A1 P48729 2/20 0.44
▸ PRMT5 O14744 1/20 0.44
▸ WDR77 Q9BQA1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30273649 0.95 CRBN (0.54) IKZF2HRH3CRBNWIZGPR119
SCHEMBL20046226 0.95 CRBN (0.54) IKZF2HRH3CRBNWIZGPR119
SCHEMBL20231489 0.91 IKZF2 (0.51) IKZF2HRH3CRBNWIZDDB1
SCHEMBL31334312 0.91 CRBN (0.49) IKZF2HRH3CRBNWIZGPR119
SCHEMBL32669075 0.90 CRBN (0.52) IKZF2CRBNWIZDDB1CSNK1A1
SCHEMBL31413474 0.90 CRBN (0.52) IKZF2CRBNWIZDDB1CSNK1A1
SCHEMBL31333603 0.89 IKZF2 (0.53) IKZF2HRH3CRBNWIZALK
SCHEMBL31334533 0.89 CRBN (0.49) IKZF2HRH3CRBNWIZALK
SCHEMBL31334319 0.88 CRBN (0.49) IKZF2CRBNWIZPRMT5WDR77
SCHEMBL31334749 0.88 CRBN (0.47) IKZF2CRBNWIZALKDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 — — EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 — — WO disclosed
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