SCHEMBL31333603

SCHEMBL31333603

CC(C)(C)OC(=O)N1CCC(CN2CCC(Oc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)CC2)CC1

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ IKZF2 Q9UKS7 9/20 0.53
▸ CRBN Q96SW2 6/20 0.47
▸ WIZ O95785 1/20 0.46
▸ IKZF1 Q13422 2/20 0.46
▸ PRMT5 O14744 1/20 0.46
▸ WDR77 Q9BQA1 1/20 0.46
▸ ESR1 P03372 2/20 0.44
▸ ALK Q9UM73 1/20 0.43
▸ HRH3 Q9Y5N1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31334749 0.93 CRBN (0.47) IKZF2CRBNWIZIKZF1PRMT5
SCHEMBL30273649 0.93 CRBN (0.54) IKZF2CRBNWIZPRMT5WDR77
SCHEMBL20046226 0.93 CRBN (0.54) IKZF2CRBNWIZPRMT5WDR77
SCHEMBL31334319 0.91 CRBN (0.49) IKZF2CRBNWIZIKZF1PRMT5
SCHEMBL31334533 0.90 CRBN (0.49) IKZF2CRBNWIZIKZF1PRMT5
SCHEMBL31334312 0.89 CRBN (0.49) IKZF2CRBNWIZPRMT5WDR77
SCHEMBL31333342 0.89 IKZF2 (0.55) IKZF2CRBNWIZPRMT5WDR77
SCHEMBL31413474 0.88 CRBN (0.52) IKZF2CRBNWIZ
SCHEMBL32669075 0.88 CRBN (0.52) IKZF2CRBNWIZ
SCHEMBL31333297 0.88 IKZF2 (0.69) IKZF2IKZF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 — — EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 — — WO disclosed
Send feedback