Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 5/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.34 |
| ▸ | CDK4 | P11802 | 3/20 | 0.34 |
| ▸ | CSF1R | P07333 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | SIK1 | P57059 | 2/20 | 0.33 |
| ▸ | SIK2 | Q9H0K1 | 2/20 | 0.33 |
| ▸ | SIK3 | Q9Y2K2 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.32 |
| ▸ | CDK9 | P50750 | 3/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333225 | 1.00 | SYK (0.36) | SYKFPR2CDK6CDK4CSF1R | |
| SCHEMBL31334216 | 1.00 | SYK (0.36) | SYKFPR2CDK6CDK4CSF1R | |
| SCHEMBL31334073 | 1.00 | SYK (0.36) | SYKFPR2CDK6CDK4CSF1R | |
| SCHEMBL31334774 | 0.96 | CDK4 (0.36) | SYKFPR2CDK6CDK4CSF1R | |
| SCHEMBL31333276 | 0.96 | CDK4 (0.36) | SYKFPR2CDK6CDK4CSF1R | |
| SCHEMBL31334706 | 0.93 | MEN1 (0.37) | SYKCDK6CDK4CSF1RMEN1 | |
| SCHEMBL31333687 | 0.93 | MEN1 (0.37) | SYKCDK6CDK4CSF1RMEN1 | |
| SCHEMBL31333256 | 0.92 | BTK (0.35) | SYKCDK6CDK4CSF1RMEN1 | |
| SCHEMBL31334833 | 0.92 | SYK (0.36) | SYKFPR2CDK6CDK4CSF1R | |
| SCHEMBL31334331 | 0.92 | SYK (0.36) | SYKFPR2CDK6CDK4CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |