SCHEMBL31333467

SCHEMBL31333467

O=C1CCC(N2Cc3cc(OC4CCN(CCC5CCNCC5)CC4)ccc3C2=O)C(=O)N1

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 7/20 0.53
▸ IKZF2 Q9UKS7 10/20 0.49
▸ WIZ O95785 2/20 0.47
▸ IKZF1 Q13422 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31334235 0.91 IKZF2 (0.57) CRBNIKZF2WIZIKZF1
SCHEMBL31334496 0.91 CRBN (0.57) CRBNIKZF2WIZ
SCHEMBL20234306 0.87 CRBN (0.65) CRBNIKZF2WIZ
SCHEMBL30273536 0.87 CRBN (0.65) CRBNIKZF2WIZ
SCHEMBL20046231 0.87 CRBN (0.65) CRBNIKZF2WIZ
SCHEMBL31334749 0.85 CRBN (0.47) CRBNIKZF2WIZIKZF1
SCHEMBL31333254 0.85 IKZF2 (0.67) IKZF2IKZF1
SCHEMBL31333471 0.85 IKZF2 (0.60) CRBNIKZF2WIZ
SCHEMBL31333321 0.85 CRBN (0.52) CRBNIKZF2WIZ
SCHEMBL22297474 0.85 CRBN (0.60) CRBNIKZF2WIZ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 — — EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 — — WO disclosed
Send feedback