SCHEMBL31334235

SCHEMBL31334235

O=C1CCC(N2Cc3cc(OC4CCN(CC5CCNCC5)CC4)ccc3C2=O)C(=O)N1

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ IKZF2 Q9UKS7 13/20 0.57
▸ CRBN Q96SW2 6/20 0.55
▸ IKZF1 Q13422 1/20 0.50
▸ WIZ O95785 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333467 0.91 CRBN (0.53) IKZF2CRBNIKZF1WIZ
SCHEMBL30183833 0.91 IKZF2 (0.52) IKZF2CRBNIKZF1WIZ
SCHEMBL22291438 0.91 IKZF2 (0.52) IKZF2CRBNIKZF1WIZ
SCHEMBL31334496 0.89 CRBN (0.57) IKZF2CRBNWIZ
SCHEMBL20234306 0.89 CRBN (0.65) IKZF2CRBNWIZ
SCHEMBL20046231 0.89 CRBN (0.65) IKZF2CRBNWIZ
SCHEMBL30273536 0.89 CRBN (0.65) IKZF2CRBNWIZ
SCHEMBL31333471 0.86 IKZF2 (0.60) IKZF2CRBNWIZ
SCHEMBL31333321 0.86 CRBN (0.52) IKZF2CRBNWIZ
SCHEMBL22297474 0.86 CRBN (0.60) IKZF2CRBNWIZ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 — — EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 — — WO disclosed
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