Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.45 |
| ▸ | LPL | P06858 | 3/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18625278 | 0.83 | DGAT1 (0.64) | DGAT1LIPGLPLKEAP1NFE2L2 | |
| SCHEMBL1180731 | 0.83 | DGAT1 (0.66) | DGAT1LIPGLPLFFAR1PKM | |
| SCHEMBL29986429 | 0.83 | DGAT1 (0.66) | DGAT1LIPGLPLFFAR1PKM | |
| SCHEMBL31091740 | 0.81 | DGAT1 (0.46) | DGAT1LIPGLPLGABRG2GABRB3 | |
| SCHEMBL12516572 | 0.81 | DGAT1 (0.57) | DGAT1LIPGLPLGABRG2GABRB3 | |
| SCHEMBL23105561 | 0.79 | DGAT1 (0.55) | DGAT1LIPGLPLHSD17B1HSD17B2 | |
| SCHEMBL29197817 | 0.78 | DGAT1 (0.55) | DGAT1LIPGLPLPKM | |
| SCHEMBL22290638 | 0.77 | LIPG (0.50) | DGAT1LIPGLPLGABRA5 | |
| SCHEMBL15197437 | 0.77 | LIPG (0.73) | DGAT1LIPGLPLKEAP1NFE2L2 | |
| SCHEMBL13700830 | 0.77 | LIPG (0.73) | DGAT1LIPGLPLKEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |