Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.36 |
| ▸ | CDK9 | P50750 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334262 | 0.90 | MAPK1 (0.41) | MAPK1CCNA2CDK2MAPK3CCNT1 | |
| SCHEMBL31333597 | 0.89 | MAPK1 (0.41) | MAPK1CCNA2CDK2MAPK3SYK | |
| SCHEMBL31335093 | 0.88 | MAPK10 (0.44) | MAPK1CCNA2CDK2MAPK3SYK | |
| SCHEMBL31334975 | 0.88 | MAPK1 (0.41) | MAPK1CCNA2CDK2MAPK3SYK | |
| SCHEMBL31334417 | 0.88 | MAPK1 (0.41) | MAPK1CCNA2CDK2MAPK3SYK | |
| SCHEMBL31334717 | 0.88 | ADORA1 (0.43) | MAPK1CCNA2CDK2MAPK3 | |
| SCHEMBL31333742 | 0.88 | MAPK1 (0.41) | MAPK1CCNA2CDK2MAPK3 | |
| SCHEMBL31334657 | 0.88 | SYK (0.47) | LMNAPOLBMAPK1TP53SYK | |
| SCHEMBL31334432 | 0.87 | MAPK1 (0.41) | MAPK1CCNA2CDK2MAPK3DYRK2 | |
| SCHEMBL31333290 | 0.86 | CDK9 (0.41) | MAPK1CCNA2CDK2MAPK3CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |