SCHEMBL31334657

SCHEMBL31334657

O=C(NC1CCC(Nc2ncc(F)c(-c3cccc(N4CCCCC4=O)c3)n2)CC1)C1CCCCC1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SYK P43405 5/20 0.47
LMNA P02545 1/20 0.45
NPC1 O15118 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
RAB9A P51151 2/20 0.44
POLB P06746 2/20 0.43
TP53 P04637 2/20 0.40
MAPK1 P28482 2/20 0.39
MAPT P10636 1/20 0.37
HPGD P15428 2/20 0.37
CPT1A P50416 2/20 0.37
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
CPT2 P23786 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31334033 0.90 SYK (0.47) SYKNPC1SMN1; SMN2RAB9AMAPK1
SCHEMBL31333530 0.89 SYK (0.49) SYKNPC1SMN1; SMN2RAB9AMAPK1
SCHEMBL31335030 0.89 SYK (0.49) SYKNPC1SMN1; SMN2RAB9AMAPK1
SCHEMBL31334567 0.88 SYK (0.50) SYKNPC1SMN1; SMN2RAB9AMAPK1
SCHEMBL31335040 0.88 SYK (0.50) SYKNPC1SMN1; SMN2RAB9AMAPK1
SCHEMBL31333712 0.88 SYK (0.47) SYKNPC1SMN1; SMN2RAB9AMAPK1
SCHEMBL31333709 0.88 LMNA (0.42) SYKLMNAPOLBTP53MAPK1
SCHEMBL31333573 0.87 SYK (0.46) SYKNPC1SMN1; SMN2RAB9AMAPK1
SCHEMBL31333482 0.86 SYK (0.48) SYKNPC1SMN1; SMN2RAB9AMAPK1
SCHEMBL31333873 0.86 SYK (0.49) SYKMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed