SCHEMBL31333711

SCHEMBL31333711

Fc1ccc(-c2cccc(-c3nc(NC4CCNCC4)ncc3Cl)c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 8/20 0.48
CCNT1 O60563 7/20 0.47
CCNK O75909 4/20 0.47
CCNE1 P24864 4/20 0.47
CDK2 P24941 4/20 0.47
CDK9 P50750 4/20 0.47
CDK12 Q9NYV4 4/20 0.47
IKBKB O14920 1/20 0.46
CDK7 P50613 2/20 0.45
CCNH P51946 2/20 0.45
MNAT1 P51948 2/20 0.45
ADORA1 P30542 3/20 0.44
PRKD3 O94806 1/20 0.43
MAP4K4 O95819 1/20 0.43
MAPK8 P45983 1/20 0.43
MAPK9 P45984 1/20 0.43
CSNK1A1 P48729 1/20 0.43
CLK2 P49760 1/20 0.43
GSK3A P49840 1/20 0.43
GSK3B P49841 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333658 0.91 ADORA1 (0.53) MAPK1CCNT1CCNKCCNE1CDK2
SCHEMBL31334428 0.91 ADORA1 (0.53) MAPK1CCNT1CCNKCCNE1CDK2
SCHEMBL31334138 0.89 MAPK8 (0.45) MAPK1CCNT1CCNKCCNE1CDK2
SCHEMBL31333534 0.89 MAPK1 (0.45) MAPK1CCNT1CCNKCCNE1CDK2
SCHEMBL31333401 0.88 MAPK1 (0.50) MAPK1CDK2MAPK8MAPK9
SCHEMBL31333514 0.88 CCNT1 (0.62) CCNT1CCNKCCNE1CDK2CDK9
SCHEMBL31334056 0.87 CCNT1 (0.57) MAPK1CCNT1CDK9CDK7CCNH
SCHEMBL31334811 0.82 MAPK1 (0.46) MAPK1CDK2MAPK8MAPK9
SCHEMBL31334614 0.82 HDAC1 (0.48) CCNT1CCNKCCNE1CDK2CDK9
SCHEMBL31334180 0.81 CCNT1 (0.47) MAPK1CCNT1ADORA1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed