SCHEMBL31334138

SCHEMBL31334138

Fc1ccc(-c2cccc(-c3nc(NC4CCNCC4)ncc3F)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK8 P45983 3/20 0.45
PRKD3 O94806 1/20 0.45
MAP4K4 O95819 1/20 0.45
MAPK1 P28482 1/20 0.45
MAPK9 P45984 1/20 0.45
CSNK1A1 P48729 1/20 0.45
CLK2 P49760 1/20 0.45
GSK3A P49840 1/20 0.45
GSK3B P49841 1/20 0.45
CSNK1G2 P78368 1/20 0.45
TAOK1 Q7L7X3 1/20 0.45
MINK1 Q8N4C8 1/20 0.45
AURKB Q96GD4 1/20 0.45
PRKD2 Q9BZL6 1/20 0.45
HIPK2 Q9H2X6 1/20 0.45
CSNK1G1 Q9HCP0 1/20 0.45
PIM2 Q9P1W9 1/20 0.45
ALK Q9UM73 1/20 0.45
CSNK1G3 Q9Y6M4 1/20 0.45
HDAC1 Q13547 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31334614 0.93 HDAC1 (0.48) MAPK8HDAC1CDK7CCNHMNAT1
SCHEMBL31333711 0.89 MAPK1 (0.48) MAPK8PRKD3MAP4K4MAPK1MAPK9
SCHEMBL31333676 0.81 CCNE1 (0.49) MAPK8MAPK1HDAC1CDK7CCNH
SCHEMBL29541062 0.81 CYP1A2 (0.53) MAPK8PRKD3MAP4K4MAPK1MAPK9
SCHEMBL31333714 0.81 DYRK2 (0.47) CDK7CCNHMNAT1CDK2CCNE1
SCHEMBL31334046 0.79 CDK9 (0.50) MAPK8MAPK9CSNK1A1CDK7CDK2
SCHEMBL31333320 0.79 ADORA1 (0.61) MAPK8MAPK9GSK3AGSK3BCDK2
SCHEMBL31333856 0.79 CDK9 (0.50) MAPK8MAPK9CSNK1A1CDK7CDK2
SCHEMBL31334200 0.79 ADORA1 (0.61) MAPK8MAPK9GSK3AGSK3BCDK2
SCHEMBL31334428 0.79 ADORA1 (0.53) MAPK1HDAC1CDK7CCNHMNAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed