SCHEMBL31333718

SCHEMBL31333718

CC1(C)OB(c2cccc(N3CCC[C@@H](O)C3)c2)OC1(C)C

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LPL P06858 2/20 0.37
LIPG Q9Y5X9 2/20 0.37
NOTUM Q6P988 1/20 0.34
SMARCA2 P51531 1/20 0.34
SMARCA4 P51532 1/20 0.34
PBRM1 Q86U86 1/20 0.34
IDH2 P48735 3/20 0.34
LRRK2 Q5S007 2/20 0.34
AR P10275 1/20 0.33
RORC P51449 1/20 0.33
KCNMA1 Q12791 1/20 0.33
AXL P30530 1/20 0.33
PIM1 P11309 1/20 0.32
PIM3 Q86V86 1/20 0.32
PIM2 Q9P1W9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31334694 1.00 LPL (0.37) LPLLIPGNOTUMSMARCA2SMARCA4
SCHEMBL30447812 0.93 AR (0.40) LPLLIPGNOTUMAR
SCHEMBL20911352 0.93 AR (0.40) LPLLIPGNOTUMAR
SCHEMBL22816331 0.86 MAPT (0.41) LPLLIPGLRRK2
SCHEMBL3021378 0.85 LPL (0.39) LPLLIPGARRORC
SCHEMBL3021381 0.85 LPL (0.39) LPLLIPGARRORC
SCHEMBL22290809 0.85 LIPG (0.40) LPLLIPGNOTUM
SCHEMBL1726528 0.83 LPL (0.44) LPLLIPG
SCHEMBL1701553 0.83 LPL (0.44) LPLLIPG
SCHEMBL3762658 0.82 LPL (0.43) LPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed