Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 5/20 | 0.49 |
| ▸ | CDK9 | P50750 | 3/20 | 0.42 |
| ▸ | CDK7 | P50613 | 2/20 | 0.42 |
| ▸ | CCNK | O75909 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.42 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.41 |
| ▸ | CAMK1D | Q8IU85 | 2/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334179 | 0.97 | SYK (0.48) | SYKCDK9CDK7CCNKCSNK1A1 | |
| SCHEMBL31333712 | 0.91 | SYK (0.47) | SYKMAPK8MAPK10MAPK9MAPK14 | |
| SCHEMBL31334567 | 0.90 | SYK (0.50) | SYKMAPK10CAMK1DCCNB2CCNE2 | |
| SCHEMBL31335040 | 0.90 | SYK (0.50) | SYKMAPK10CAMK1DCCNB2CCNE2 | |
| SCHEMBL31334120 | 0.89 | SYK (0.45) | SYKCDK9CDK7MAPK8CCNB2 | |
| SCHEMBL31333530 | 0.89 | SYK (0.49) | SYKMAPK10CAMK1DCCNB2CCNE2 | |
| SCHEMBL31335030 | 0.89 | SYK (0.49) | SYKMAPK10CAMK1DCCNB2CCNE2 | |
| SCHEMBL31334033 | 0.88 | SYK (0.47) | SYKCDK9CDK7MAPK8MAPK10 | |
| SCHEMBL31334814 | 0.87 | SYK (0.49) | SYKMAPK9CAMK1DCCNB2CCNE2 | |
| SCHEMBL31333681 | 0.87 | MAP4K1 (0.46) | CDK9CDK7CCNKCSNK1A1CDK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |