SCHEMBL31334567

SCHEMBL31334567

NC(=O)[C@H]1CC[C@H](Nc2ncc(F)c(-c3cccc(N4CCCCC4=O)c3)n2)CC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SYK P43405 5/20 0.50
MAPK1 P28482 3/20 0.40
CAMK1D Q8IU85 2/20 0.40
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CDK2 P24941 5/20 0.38
CDK1 P06493 2/20 0.38
CDK4 P11802 1/20 0.38
CCND1 P24385 1/20 0.38
CCNA2 P20248 3/20 0.38
CCNA1 P78396 2/20 0.38
JUN P05412 1/20 0.38
MAPK10 P53779 1/20 0.38
AURKA O14965 1/20 0.38
MAPK6 Q16659 1/20 0.38
HRH3 Q9Y5N1 1/20 0.38
DYRK2 Q92630 1/20 0.37
CCNB2 O95067 1/20 0.37
CCNE2 O96020 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31335040 1.00 SYK (0.50) SYKMAPK1CAMK1DNPC1RAB9A
SCHEMBL31334814 0.97 SYK (0.49) SYKMAPK1CAMK1DNPC1RAB9A
SCHEMBL31335030 0.92 SYK (0.49) SYKMAPK1CAMK1DNPC1RAB9A
SCHEMBL31333530 0.92 SYK (0.49) SYKMAPK1CAMK1DNPC1RAB9A
SCHEMBL31333680 0.90 SYK (0.46) SYKMAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL31333482 0.90 SYK (0.48) SYKMAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL31333873 0.90 SYK (0.49) SYKMAPK1CAMK1DCDK2CDK1
SCHEMBL31333712 0.90 SYK (0.47) SYKMAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL31334552 0.89 SYK (0.44) SYKMAPK1CAMK1DJUNMAPK10
SCHEMBL31334033 0.88 SYK (0.47) SYKMAPK1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed