SCHEMBL31333904

SCHEMBL31333904

CC(C)(C)OC(=O)N1CCC(CCN2CCC(c3ccc4c(c3)oc(=O)n4C3CCC(=O)NC3=O)CC2)CC1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 9/20 0.47
CRBN Q96SW2 9/20 0.47
KDM4E B2RXH2 1/20 0.39
MAPT P10636 1/20 0.39
THRB P10828 1/20 0.39
GPR119 Q8TDV5 4/20 0.39
NAMPT P43490 1/20 0.38
ASAH1 Q13510 4/20 0.38
FAAH O00519 1/20 0.38
NAAA Q02083 1/20 0.38
IKZF2 Q9UKS7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333308 0.93 DDB1 (0.48) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL23541035 0.92 DDB1 (0.54) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL31334918 0.89 DDB1 (0.44) DDB1CRBNASAH1FAAHNAAA
SCHEMBL31333265 0.88 CRBN (0.47) DDB1CRBNGPR119
SCHEMBL31333843 0.88 DDB1 (0.50) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL31323649 0.86 DDB1 (0.49) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL23540560 0.86 DDB1 (0.41) DDB1CRBNASAH1FAAHNAAA
SCHEMBL31333187 0.84 IKZF2 (0.41) DDB1CRBNASAH1FAAHNAAA
SCHEMBL31333377 0.83 IKZF2 (0.40) DDB1CRBNASAH1FAAHNAAA
SCHEMBL31333525 0.81 CRBN (0.48) DDB1CRBNGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed