SCHEMBL31333377

SCHEMBL31333377

CC(C)(C)OC(=O)CCN1CCC(N2CCC(c3ccc4c(c3)oc(=O)n4C3CCC(=O)NC3=O)CC2)CC1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
IKZF2 Q9UKS7 3/20 0.40
ASAH1 Q13510 7/20 0.38
FAAH O00519 1/20 0.38
NAAA Q02083 1/20 0.38
DDB1 Q16531 3/20 0.37
CRBN Q96SW2 3/20 0.37
TSHR P16473 1/20 0.36
IKZF1 Q13422 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333347 0.89 IKZF2 (0.40) IKZF2ASAH1FAAHNAAADDB1
SCHEMBL23540560 0.88 DDB1 (0.41) IKZF2ASAH1FAAHNAAADDB1
SCHEMBL31333843 0.87 DDB1 (0.50) IKZF2DDB1CRBN
SCHEMBL31334185 0.87 DDB1 (0.46) IKZF2DDB1CRBNIKZF1
SCHEMBL31334423 0.84 DDB1 (0.41) IKZF2ASAH1FAAHNAAADDB1
SCHEMBL31333904 0.83 DDB1 (0.47) IKZF2ASAH1FAAHNAAADDB1
SCHEMBL23541035 0.82 DDB1 (0.54) ASAH1FAAHNAAADDB1CRBN
SCHEMBL22502565 0.81 DDB1 (0.50) IKZF2DDB1CRBNIKZF1
SCHEMBL31334918 0.81 DDB1 (0.44) IKZF2ASAH1FAAHNAAADDB1
SCHEMBL31334711 0.81 IKZF2 (0.45) IKZF2ASAH1FAAHNAAADDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed