SCHEMBL31333843

SCHEMBL31333843

CC(C)(C)OC(=O)N1CCC(N2CCC(c3ccc4c(c3)oc(=O)n4C3CCC(=O)NC3=O)CC2)CC1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 12/20 0.50
CRBN Q96SW2 12/20 0.50
IKZF2 Q9UKS7 1/20 0.42
KDM4E B2RXH2 1/20 0.41
MAPT P10636 1/20 0.41
THRB P10828 1/20 0.41
HRH3 Q9Y5N1 3/20 0.41
GPR119 Q8TDV5 1/20 0.39
NAMPT P43490 1/20 0.39
OPRM1 P35372 1/20 0.37
OPRD1 P41143 1/20 0.37
OGFRL1 Q5TC84 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23541035 0.95 DDB1 (0.54) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL31333308 0.88 DDB1 (0.48) DDB1CRBNIKZF2KDM4EMAPT
SCHEMBL31333904 0.88 DDB1 (0.47) DDB1CRBNIKZF2KDM4EMAPT
SCHEMBL31333377 0.87 IKZF2 (0.40) DDB1CRBNIKZF2
SCHEMBL31334423 0.86 DDB1 (0.41) DDB1CRBNIKZF2
SCHEMBL29579240 0.85 DDB1 (0.51) DDB1CRBNIKZF2KDM4EMAPT
SCHEMBL24480442 0.85 DDB1 (0.51) DDB1CRBNIKZF2KDM4EMAPT
SCHEMBL31334918 0.84 DDB1 (0.44) DDB1CRBNIKZF2
SCHEMBL31334711 0.84 IKZF2 (0.45) DDB1CRBNIKZF2
SCHEMBL23540560 0.84 DDB1 (0.41) DDB1CRBNIKZF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed