Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.49 |
| ▸ | BCL6 | P41182 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CDK7 | P50613 | 2/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333763 | 0.89 | CDK9 (0.47) | ADORA1MAPK8CCNE1CDK2CDK7 | |
| SCHEMBL31333951 | 0.89 | ADORA1 (0.41) | ADORA1CCNE1CDK2CDK7CDK9 | |
| SCHEMBL31333233 | 0.85 | NPC1 (0.43) | ADORA1CCNE1CDK2ADORA2ACCNB2 | |
| SCHEMBL31333197 | 0.84 | MAPK3 (0.41) | ADORA1CCNE1CDK2ADORA2ACCNB2 | |
| SCHEMBL31334783 | 0.84 | MAPK8 (0.45) | ADORA1MAPK8CCNE1CDK2ADORA2A | |
| SCHEMBL31333828 | 0.82 | MAPK3 (0.43) | ADORA1CCNE1CDK2CDK7CDK9 | |
| SCHEMBL31333561 | 0.82 | MAPK3 (0.43) | ADORA1CCNE1CDK2CDK7CDK9 | |
| SCHEMBL31334771 | 0.82 | SYK (0.42) | ADORA1MAPK8CCNE1CDK2CDK7 | |
| SCHEMBL19078915 | 0.76 | NOTUM (0.37) | KMT2AKDM4E | |
| SCHEMBL30919870 | 0.76 | NOTUM (0.37) | KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |