Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 4/20 | 0.42 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | CD38 | P28907 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 3/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.36 |
| ▸ | CDK2 | P24941 | 3/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.36 |
| ▸ | CCNK | O75909 | 2/20 | 0.36 |
| ▸ | CDK9 | P50750 | 2/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.36 |
| ▸ | CCNH | P51946 | 1/20 | 0.35 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334502 | 0.93 | MAPK3 (0.39) | SYKMAPK3ADORA1CD38CDK7 | |
| SCHEMBL31333828 | 0.91 | MAPK3 (0.43) | MAPK3ADORA1CDK7CCNE1CDK2 | |
| SCHEMBL31333561 | 0.91 | MAPK3 (0.43) | MAPK3ADORA1CDK7CCNE1CDK2 | |
| SCHEMBL31333422 | 0.89 | MAPK3 (0.44) | SYKMAPK3ADORA1CD38CDK7 | |
| SCHEMBL31333355 | 0.89 | BTK (0.47) | SYKMAPK3MAPK1DYRK2 | |
| SCHEMBL31333197 | 0.87 | MAPK3 (0.41) | MAPK3ADORA1CCNE1CDK2MAPK1 | |
| SCHEMBL31334543 | 0.84 | SYK (0.44) | SYKMAPK3CDK7CDK2CCNT1 | |
| SCHEMBL31334731 | 0.84 | MAPK3 (0.41) | MAPK3ADORA1CDK7CDK2MAPK1 | |
| SCHEMBL31335048 | 0.84 | MAPK3 (0.41) | MAPK3ADORA1CDK7CDK2MAPK1 | |
| SCHEMBL31333944 | 0.82 | ADORA1 (0.49) | ADORA1CDK7MAPK8CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |