Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK2 | Q92630 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 2/20 | 0.42 |
| ▸ | CCND1 | P24385 | 2/20 | 0.42 |
| ▸ | CCND3 | P30281 | 1/20 | 0.42 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | IDH2 | P48735 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.39 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334516 | 0.93 | MAPK1 (0.48) | DYRK2MAPK1CDK4CCND1CCND3 | |
| SCHEMBL31333588 | 0.89 | CDK4 (0.48) | DYRK2MAPK1CDK4CCND1CCND3 | |
| SCHEMBL31334210 | 0.87 | MAPK1 (0.40) | MAPK1CDK4CCND1SYKCDK1 | |
| SCHEMBL31334824 | 0.87 | MAPK1 (0.44) | DYRK2MAPK1CDK4CCND1CCND3 | |
| SCHEMBL31333632 | 0.87 | SYK (0.39) | DYRK2MAPK1CDK4CCND1CCND3 | |
| SCHEMBL31334846 | 0.86 | DYRK2 (0.42) | DYRK2MAPK1CDK4CCND1CCND3 | |
| SCHEMBL31334878 | 0.86 | MAPK1 (0.41) | DYRK2MAPK1CDK4CCND1CCND3 | |
| SCHEMBL31334367 | 0.84 | MAPK1 (0.49) | MAPK1USP30CCNT1CDK2 | |
| SCHEMBL31335118 | 0.82 | MAPK14 (0.46) | DYRK2MAPK1CDK4CCND1CCND3 | |
| SCHEMBL31333648 | 0.82 | MAPK1 (0.48) | DYRK2MAPK1CDK4CCND1CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |