SCHEMBL31334846

SCHEMBL31334846

CC(C)(C)OC(=O)N1CC2(CC(OC(=O)N3CCC(Nc4ncc(F)c(-c5cccc(-n6ccccc6=O)c5)n4)CC3)C2)C1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DYRK2 Q92630 6/20 0.42
MAPK1 P28482 1/20 0.42
CDK4 P11802 1/20 0.40
CCND1 P24385 1/20 0.40
CCND3 P30281 1/20 0.40
CDK6 Q00534 1/20 0.40
USP30 Q70CQ3 2/20 0.39
VCP P55072 2/20 0.38
IDH1 O75874 1/20 0.38
IDH2 P48735 1/20 0.38
HPGDS O60760 2/20 0.37
CCNT1 O60563 1/20 0.37
SYK P43405 2/20 0.37
ALK Q9UM73 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31334516 0.91 MAPK1 (0.48) DYRK2MAPK1CDK4CCND1CCND3
SCHEMBL31333252 0.89 DYRK2 (0.40) DYRK2MAPK1CDK4CCND1CCND3
SCHEMBL31334158 0.88 SYK (0.39) DYRK2MAPK1CDK4CCND1SYK
SCHEMBL31333588 0.87 CDK4 (0.48) DYRK2MAPK1CDK4CCND1CCND3
SCHEMBL31333949 0.86 DYRK2 (0.43) DYRK2MAPK1CDK4CCND1CCND3
SCHEMBL31334824 0.85 MAPK1 (0.44) DYRK2MAPK1CDK4CCND1CCND3
SCHEMBL31334878 0.84 MAPK1 (0.41) DYRK2MAPK1CDK4CCND1CCND3
SCHEMBL31334367 0.83 MAPK1 (0.49) MAPK1USP30CCNT1
SCHEMBL31333229 0.82 CDK2 (0.39) MAPK1CDK4CCND1SYK
SCHEMBL31334956 0.82 CDK2 (0.39) MAPK1CDK4CCND1SYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed