Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | UBE2N | P61088 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25694585 | 0.77 | SMN1; SMN2 (0.43) | KMT2AMAPTL3MBTL1KCNH2RPS6KA5 | |
| SCHEMBL31334291 | 0.76 | GRM4 (0.45) | MAPTKDM4EKCNH2RXRAGRIN1 | |
| SCHEMBL30919726 | 0.75 | HTT (0.46) | MAPTHTTPKML3MBTL1RPS6KA5 | |
| SCHEMBL31333439 | 0.74 | MAPT (0.32) | KMT2AMAPTRPS6KA5SMN1; SMN2 | |
| SCHEMBL1961169 | 0.74 | KMT2A (0.39) | KMT2AMAPTHTTPKML3MBTL1 | |
| SCHEMBL1960427 | 0.69 | KMT2A (0.40) | KMT2AMAPTHTTPKML3MBTL1 | |
| SCHEMBL24053367 | 0.68 | RORC (0.35) | MAPTKCNH2RPS6KA5GRIN1GRIN2B | |
| SCHEMBL31333607 | 0.68 | ADORA2A (0.39) | KMT2AMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL31333543 | 0.68 | GRM4 (0.45) | KDM4ERXRAGRIN1GRIN2BSMN1; SMN2 | |
| SCHEMBL19120907 | 0.67 | FLT3 (0.61) | KMT2AHTTPKML3MBTL1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |