Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 5/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MELK | Q14680 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333543 | 0.89 | GRM4 (0.45) | GRM4KDM5BDYRK1BAXLMAP4K4 | |
| SCHEMBL31334034 | 0.76 | KMT2A (0.38) | KDM4ESMN1; SMN2MAPTRXRAGRIN1 | |
| SCHEMBL17059212 | 0.75 | CCNE2 (0.49) | KDM5BAXLSMN1; SMN2MAPT | |
| SCHEMBL31333607 | 0.75 | ADORA2A (0.39) | SMN1; SMN2MAPT | |
| SCHEMBL30919697 | 0.74 | GRM4 (0.51) | GRM4KDM5BAXLKDM4ESMN1; SMN2 | |
| SCHEMBL31489235 | 0.72 | CCNE2 (0.33) | KDM4ESMN1; SMN2 | |
| SCHEMBL16513605 | 0.70 | JAK2 (0.45) | MAPT | |
| SCHEMBL31333468 | 0.70 | BTK (0.38) | MAPT | |
| SCHEMBL22852543 | 0.69 | KDM5B (0.41) | KDM5BSMN1; SMN2KCNH2 | |
| SCHEMBL29607254 | 0.69 | KDM5B (0.41) | KDM5BSMN1; SMN2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |