SCHEMBL31334061

SCHEMBL31334061

CC(=O)N[C@H]1CC[C@H](Nc2ncc(F)c(-c3cccc(C(=O)N4CC[C@H](O)C4)c3)n2)CC1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ATR Q13535 1/20 0.45
CCNK O75909 4/20 0.44
CDK12 Q9NYV4 4/20 0.44
DYRK2 Q92630 8/20 0.43
CDK6 Q00534 3/20 0.43
CDK4 P11802 1/20 0.43
LRRK2 Q5S007 1/20 0.42
CCNA2 P20248 2/20 0.41
CDK2 P24941 2/20 0.41
CDK7 P50613 2/20 0.41
CCNH P51946 2/20 0.41
MNAT1 P51948 2/20 0.41
PDE4B Q07343 1/20 0.41
VNN1 O95497 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31333850 0.92 ATR (0.47) ATRCCNKCDK12DYRK2CDK6
SCHEMBL31334011 0.92 DYRK2 (0.49) ATRCCNKCDK12DYRK2CDK6
SCHEMBL31334503 0.92 DYRK2 (0.49) ATRCCNKCDK12DYRK2CDK6
SCHEMBL31334870 0.90 ATR (0.48) ATRCCNKCDK12DYRK2CDK6
SCHEMBL31334992 0.90 CCNK (0.49) ATRCCNKCDK12DYRK2CDK6
SCHEMBL31335052 0.89 ATR (0.47) ATRCCNKCDK12DYRK2CDK6
SCHEMBL31333517 0.89 ATR (0.47) ATRCCNKCDK12DYRK2CDK6
SCHEMBL31333542 0.89 MERTK (0.46) ATRCCNKCDK12DYRK2CDK6
SCHEMBL31334370 0.88 ATR (0.47) ATRCCNKCDK12DYRK2CDK6
SCHEMBL31333202 0.87 DYRK2 (0.48) CCNKCDK12DYRK2CDK6CDK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed