Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 2/20 | 0.47 |
| ▸ | CCNK | O75909 | 5/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 5/20 | 0.44 |
| ▸ | DYRK2 | Q92630 | 5/20 | 0.43 |
| ▸ | CDK4 | P11802 | 2/20 | 0.42 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.41 |
| ▸ | CDK2 | P24941 | 5/20 | 0.41 |
| ▸ | CDK7 | P50613 | 3/20 | 0.41 |
| ▸ | CCNH | P51946 | 3/20 | 0.41 |
| ▸ | MNAT1 | P51948 | 3/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333517 | 0.92 | ATR (0.47) | ATRCCNKCDK12DYRK2CDK4 | |
| SCHEMBL31335052 | 0.92 | ATR (0.47) | ATRCCNKCDK12DYRK2CDK4 | |
| SCHEMBL31334870 | 0.92 | ATR (0.48) | ATRCCNKCDK12DYRK2CDK4 | |
| SCHEMBL31334992 | 0.90 | CCNK (0.49) | ATRCCNKCDK12DYRK2CDK4 | |
| SCHEMBL31333850 | 0.89 | ATR (0.47) | ATRCCNKCDK12DYRK2CDK4 | |
| SCHEMBL31334061 | 0.88 | ATR (0.45) | ATRCCNKCDK12DYRK2CDK4 | |
| SCHEMBL31334503 | 0.88 | DYRK2 (0.49) | ATRCCNKCDK12DYRK2CDK4 | |
| SCHEMBL31334011 | 0.88 | DYRK2 (0.49) | ATRCCNKCDK12DYRK2CDK4 | |
| SCHEMBL31333642 | 0.87 | DYRK2 (0.45) | ATRCCNKCDK12DYRK2CDK4 | |
| SCHEMBL31335015 | 0.84 | SYK (0.44) | CCNKCDK4CDK6CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |