Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 4/20 | 0.40 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19078912 | 1.00 | MAPT (0.42) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL31333468 | 0.91 | BTK (0.38) | MAPTBTKADORA1CYP11B1CYP11B2 | |
| SCHEMBL3758203 | 0.88 | KDM4E (0.52) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL13550200 | 0.88 | CYP11B1 (0.44) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL15577176 | 0.85 | BTK (0.46) | MAPTALDH1A1KDM4EBTKMEN1 | |
| SCHEMBL29967741 | 0.83 | BTK (0.52) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL27177141 | 0.83 | BTK (0.52) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL30919617 | 0.83 | BTK (0.52) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL13120752 | 0.83 | BIRC5 (0.42) | MAPTALDH1A1HPGDSMN1; SMN2BTK | |
| SCHEMBL31333216 | 0.80 | LOXL2 (0.47) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |